Submit Overview and References Appropriate Usage

Appropriate Usage of TMBpro

TMBpro assumes that the sequence is for a TMB protein. TMBpro does not contain a screening component or predict the probability that a given protein really is a TMB protein. It is a specialized predictor and not a general purpose tertiary structure predictor. For any protein you submit, including globular, TMBpro will predict the secondary structure, contacts, and then build a model utilizing available TMB templates. If the protein is not a TMB protein then the model is destined to be wrong. To use TMBpro appropriately you should first have some evidence that your sequence is a TMB protein.

TMB Screening Methods

A variety of methods have been developed for discriminating TMB from non-TMB proteins. We have confirmed the following methods were functioning as of 11-24-2008:

Contact TMBpro Administrator: arandall@ics.uci.edu

Institute for Genomics and Bioinformatics
School of Information & Computer Science
University of California Irvine